Endocrine Abstracts

IntroductionPartial gonadal dysgenesis (PGD) is one of the rare 46, XY disorders of sex development (DSD), associated with variable degrees of impaired testicular development and function. Phenotypic appearance is related to the level of functional testicular hormones. Usually PGD is diagnosed in infancy because of significant genital anomaly at birth, however, spontaneous puberty is seen in up to 57% of all 46, XY PGD cases. Bilateral gonadectomy is per...

Endocrinopathies are one of the most common side effects induced by immunotherapy. The side effects result from the activation of immune system, which affects not only cancerous but also healthy body cells. In most cases, only one endocrinopathy occurs, but in our presented case we describe multiple endocrinopathies that occurred to a one person. 53-years-old male patient was referred to the Emergency department due to severe hyperglycemia (37.13 mmol/l) and the following symp...

Background: Data on the effects of long term glucocorticoid (GC) treatment on bone mineral density (BMD) in patients with congenital adrenal hyperplasia (CAH) are controversial. Objectives: To evaluate BMD and vitamin D status in adolescents and young adults with CAH in comparison with healthy controls.Methods: 32 patients with classical CAH (13 males; mean of age 26.0±7.1 years (14.0–37.3) were compared to 32 healthy con...